Author/Authors :
Fayaz, Ahmad Center For Research and Reference on Rubies - Pasteur Institute, Tehran , Farahtaj, Firouzeh Center For Research and Reference on Rubies - Pasteur Institute, Tehran , Eslami, Naser Center For Research and Reference on Rubies - Pasteur Institute, Tehran , Howaizi, Nader Center For Research and Reference on Rubies - Pasteur Institute, Tehran , Biglari, Peyvand Center For Research and Reference on Rubies - Pasteur Institute, Tehran , Janani Susan Simani, Alireza Center For Research and Reference on Rubies - Pasteur Institute, Tehran
Abstract :
Rabies is a fatal disease, which is the most important viral zoonosis from a global perspective. Human rabies encephalitis still remains a serious public health problem in developing countries such as Iran, which had only 45 human rabies cases during 2000-2006. In this regard, epidemiological studies on bite injuries, animal and local situation would provide a useful and accessible source of epidemiological information. This data could be used effectively to enhance rabies surveillance in human populations, trends of the disease incidence and improve the allocation of medical resources and assess the effectiveness of rabies control measures implemented against rabies. In this study, we present and discuss human rabies cases who suffered severe face, head, neck, arm and legs injuries when attacked by a rabid animal and also suggest a hypothesis concerning possible causes of death from rabies 23 brain samples of rabid individuals from different parts of Iran have been diagnosed by FAT and MNT methods. Kerman province had the highest rate of human rabies in Iran and dog bites is the most common source of infection, although in mountainous area, dog and wolf have been considered the reservoir of the disease. The data also suggest the route of entering of rabies virus and the degree of postexposure treatment a patient receives could predict the outcome of the disease and fate of patients.
