Author/Authors :
GUO, Yue School of Medicine - Huzhou University, Huzhou, China , ZHOU, Hong Chang School of Medicine - Huzhou University, Huzhou, China , DONG, Ying School of Medicine - Huzhou University, Huzhou, China , ZHANG, Ting School of Medicine - Huzhou University, Huzhou, China , SUN, Yu Yang School of Medicine - Huzhou University, Huzhou, China , ZHONG, Jian Feng Infectious Diseases Dept. - Huzhou Central Hospital, Huzhou, China , CAO, Yu Liang Intensive Medicine - Hospital of PLA, Huzhou, Zhejiang, China , SHAO, Sheng Wen School of Medicine - Huzhou University, Huzhou, China , PAN, Yong Liang School of Medicine - Huzhou University, Huzhou, China , DONG, Hai Yan School of Medicine - Huzhou University, Huzhou, China
Abstract :
Background: Pomacea canaliculata (P.canaliculata) lung nodules, were commonly
caused by Angiostrongylus cantonensis infection. Here, we found a new nodule type
without any parasites.
Methods: Overall, 447 P. canaliculata snails were collected in Ning Bo, Zhe Jiang,
China in 2018. In order to exhibit the similarities and differences between two nodules
types (2018, Huzhou Zhejiang, China), both types were collected in formalin
for tissue pathological sectioning. Besides, to obtain the microbial community of
the new nodule, the 18S ribosomal RNA (rRNA) gene of it was amplified and analyzed
using the Illumina second-generation sequencing platform.
Results: Although two nodules were found in the lungs of P. canaliculata, they were
different in shape and pathology. Illumina sequencing indicated Poterioochromonas sp.,
a species of golden algae, might be the causing agent of the new nodule.
Conclusion: We firstly found a new pathological nodule type in the lungs of P.
canaliculata, and this nodule might be induced by golden algae infection, however,
the direct link between the golden algae and the new nodules, as well as the nodules’
impact on the snails’ physiology and A. cantonensis infection require further study.
Keywords :
Pomacea canaliculata , Lung nodule , 18S ribosomal RNA , Poterioochromonas sp. Angiostrongylus cantonensis
