Author/Authors :
GUPTA, J. K. Institute of Pharmaceutical Research, Mathura, India , MISHRA, P. Institute of Pharmaceutical Research, Mathura, India , RANI, A. College of Pharmacy, Jaipur, Rajasthan, India , MITRA MAZUMDER, P. Birla Institute of Technology, Mesra, Ranchi, Jharkhand, India
Abstract :
The present investigation explores the blood glucose lowering potential of Berberis aristata stem bark
extract (methanolic extract) in alloxan-induced diabetic rats as well as its in vitro antioxidant property. It is
observed that methanolic extract of B. aristata stem bark exhibits significant antidiabetic activity in a dosedependent
manner, but not better than glibenclamide. The extract also has enough reducing power to
manifest its antioxidant nature.
Keywords :
Antidiabetc activity , Antioxidant , Berberis aristata , Methanolic extract , Phenolic content , Alloxan
