Title of article :
Temporary Worsening of Kidney Function Following Aortic Reconstructive Surgery
Author/Authors :
Ghaheri, Hafez Department of Surgery - Shahrekord University of Medical Sciences , Kazemzadeh, Gholam Hossein Department of Surgery - Mashhad University of Medical Sciences , Beigi, Ali Akbar Department of Surgery - Isfahan University of Medical Sciences
Abstract :
Introduction. Little is known about the incidence of temporary
kidney dysfunction following major vascular surgeries. We aimed
to assess the frequency of temporary decreased kidney function
following aortic surgeries.
Materials and Methods. In a retrospective study, we assessed
108 hospital records of the patients who had undergone elective
open abdominal surgery of aortic aneurysm. Preoperative and
postoperative (days 1, 2, and 3) data on estimated glomerular
filtration rate (GFR) were collected and evaluated in relation to the
patients’ clinical characteristics and outcomes. A decline greater
than 10% in GFR on day 1 or 2, and then, an increase of GFR to
a level of maximum 10% below the baseline value on the third
postoperative day was considered as temporary worsening of
kidney function. Postoperative alterations of GFR not greater than
10% in relation to the baseline were considered as improved or
unchanged kidney function. Two patients with persistent decrease
in GFR were excluded.
Results. Temporary worsening of kidney function was seen in 25
patients (23.6%). Short-term mortality rate was 44.0% in this group
of patients, while it was 17.3% in those without decreased GFR
(P = .006). According to the regression analysis, the only predictor
of mortality was temporary worsening of kidney function, with a
hazard ratio of 4.03 (95% confidence interval, 1.44 to 11.31; P = .008).
Conclusions. Nearly 1 out of 4 aortic surgeries results in kidney
dysfunction. Albeit temporary in most cases, it seems to be associated
with a higher short-term mortality rate.
Keywords :
kidney function , aneurysm , vascular surgical procedures , cardiovascular diseases
Journal title :
Astroparticle Physics