Title of article :
Evaluation of HTLV-1 in Human Subgingival Plaque of Seropositive Patients
Author/Authors :
Sargolzaee, N Department of Periodontics - School of Dentistry - Mashhad University of Medical Sciences , Arab, HR Department of Periodontics - School of Dentistry - Mashhad University of Medical Sciences , Moeintaghavi, A Department of Periodontics - School of Dentistry - Mashhad University of Medical Sciences , Radvar, M Department of Periodontics - School of Dentistry - Mashhad University of Medical Sciences
Abstract :
Objective: The aim of this study was to investigate the existence of human T-lymphotropic virus type 1 (HTLV-1) in subgingival plaque of HTLV-1 seropositive pa-tients.
Materials and Methods: A total of 18 patients including 13 females and fivemales, with a mean age of 37 years participated in this descriptive study. Half of them were HTLV-1 carriers and the others were in HTLV-1 associated myelopathy tropical spastic paraparesia (HAM/TSP) stage.Subgingival dental plaque samples were taken using sterile paper points and examined to detect HTLV-1 using polymerase chain reaction (PCR).
Results: None of the carrier stage patients revealed HTLV-1 virus, while only one patient in the HAM/TSP group was found with the virus.
Conclusion: This study showed that the existence of HTLV-1 virus in subgingival plaque of patients suffering from HTLV-1 in carrier and HAM/TSP stages with healthy periodon-tium is rare. Studies with larger samples are recommended.
Keywords :
Human T-lymphotropic virus 1 , Dental Plaque , Polymerase Chain Reaction
Journal title :
Astroparticle Physics
