Author/Authors :
Alavi Darazam, Ilad National Research Institute of Tuberculosis and Lung Diseases - Shahid Beheshti University of Medical Sciences, Tehran, IR Iran , Shamaei, Masoud National Research Institute of Tuberculosis and Lung Diseases - Shahid Beheshti University of Medical Sciences, Tehran, IR Iran , Mobarhan, Mandana National Research Institute of Tuberculosis and Lung Diseases - Shahid Beheshti University of Medical Sciences, Tehran, IR Iran , Ghasemi, Shahin Internal Medicine Department - Tehran University of Medical Sciences, Tehran, IR Iran , Tabarsi, Payam National Research Institute of Tuberculosis and Lung Diseases - Shahid Beheshti University of Medical Sciences, Tehran, IR Iran , Motavasseli, Masoud National Research Institute of Tuberculosis and Lung Diseases - Shahid Beheshti University of Medical Sciences, Tehran, IR Iran , Mansouri, Davood National Research Institute of Tuberculosis and Lung Diseases - Shahid Beheshti University of Medical Sciences, Tehran, IR Iran
Abstract :
Nocardiosis has been reported increasingly in recent two decades, probably due to improvement in isolation of the organism and increased
burden of immune compromised patients. Nocardia occasionally has been reported in healthy people. A case series of definitive Nocardiosis
(2002 to 2010), clinical characteristics, underlying diseases, immune status and in-patient outcome were studied in a tertiary referral
center. Twenty one patients with definite diagnosis of Nocardiosis were studied. 17 cases (81%) had an underlying disease (diabetes mellitus,
corticosteroid therapy, and chronic granulomatous disease and collagen vascular diseases). Four patients (19%) were immune-competent
without any predisposing disease. In 17 patients (81%), Nocardiosis was limited to respiratory tract and in 4 cases (19%) it was disseminated
with multi organ involvement. Two cases (9.5%) died in hospital.
Keywords :
Nocardia Infections , Immunocompromised Host , Treatment Outcome , Nocardiosis , Cutaneous
