مرکز منطقه ای اطلاع رساني علوم و فناوري - Outcomes of Single Segment Implantation of Conventional Intacs versus Intacs SK for Keratoconus

Author/Authors :

Hashemian, Mohammad Nasser Cornea Department - Eye Research Center - Farabi Eye Hospital - Tehran University of Medical Sciences , Zare, Mohammad Ali Cornea Department - Eye Research Center - Farabi Eye Hospital - Tehran University of Medical Sciences , Mohammadpour, Mehrdad Cornea Department - Eye Research Center - Farabi Eye Hospital -Tehran University of Medical Sciences , Rahimi, Firouzeh Cornea Department - Eye Research Center - Farabi Eye Hospital - Tehran University of Medical Sciences , Fallah, Mohammad Reza Cornea Department - Eye Research Center - Farabi Eye Hospital - Tehran University of Medical Sciences , Keramat Panah, Fereydoun Cornea Department - Eye Research Center - Farabi Eye Hospital - Tehran University of Medical Sciences

Abstract :

Purpose: To compare the visual, refractive, and keratometric outcomes of single‑segment conventional and severe keratoconus (SK) types of Intacs for correction of inferior keratoconus (KCN). Methods: A total number of 41 consecutive eyes of 23 patients with a diagnosis of inferior KCN underwent Intacs implantation. Eight eyes were excluded due to postoperative complications (4 eyes) and loss to follow‑up (4 eyes) and finally 33 eyes underwent statistical analysis. Two groups were created according to Intacs type insertion; conventional group (17 eyes) and SK groups (16 eyes). Intracorneal ring segments (ICRS) implantation was indicated in keratoconic patients with contact‑lens intolerance or reduced best spectacle‑corrected visual acuity (BSCVA). Results: In the conventional group, mean uncorrected distance visual acuity (UCDVA) improved from 0.45 ± 0.41 preoperatively to 0.69 ± 0.39 six months after surgery representing a gain of 2 Snellen lines, and in the SK group mean UCDVA changed from 0.40 ± 0.35 preoperatively to 0.58 ± 0.48 equivalent to two Snellen lines improvement 6 months after operation (P = 0.48). Mean preoperative BSCVA in the conventional group improved from 0.72 ± 0.41 to 0.86 ± 0.39 (2 lines improvement) postoperatively and in the SK group improved from 0.71 ± 0.69 to 0.75 ± 0.45 (0.50 line improvement) ( P = 0.29). Mean preoperative spherical equivalent (SE) decreased from −4.86 ± 2.26 D to −3.57 ± 2.21 D (conventional group) and from −4.20 ± 1.82 D to −3.60 ± 1.89 D (P = 0.34), mean astigmatism (AST) decreased from −5.20 ± 2.07 D and −4.50 ± 2.26 D to −4.02 ± 2.57 D and − 3.18 ± 2.14 D in the conventional and SK groups, respectively (P = 0.68). Finally, mean K min decreased from 47.11 ± 2.51 D to 45.40 ± 3.30 D in the conventional group and from 45.05 ± 2.59 D to 44 ± 3.88 D in the SK group (P = 0.63) and mean K max was decreased from 52.82 ± 3.23 D to 50.52 ± 3.57 D and from 49.72 ± 3.17 D to 48.55 ± 4.50 D, respectively (P = 0.48). Conclusion: Single‑segment implantation of conventional and SK Intacs improved UCDVA and BSCVA, decreased corneal AST and keratometry in both groups with comparable outcomes.