Title of article :
Association between HTLV-I Infection and Chronic Lupoid Leishmaniasis
Author/Authors :
Pezeshkpoor, Fakhrozaman Cutaneous Leishmanaisis Research Center -Ghaem Hospital - School of Medicine - Mashhad University of Medical Sciences , Rezaei, Abdol Rahim HTLV-I Foundation - Immunology Department - Mashhad University of Medical Sciences , Shirdel, Abbas Department of Internal Medicine - Mashhad University of Medical Sciences , Khaje daluee, Mohammad Department of Social Medicine - Mashhad University of Medical Sciences , Alizadeh, Mansoreh Cutaneous Leishmanaisis Research Center -Ghaem Hospital - School of Medicine - Mashhad University of Medical Sciences , Yazdanpanah, Mohammad Javad Cutaneous Leishmanaisis Research Center -Ghaem Hospital - School of Medicine - Mashhad University of Medical Sciences
Abstract :
Objective(s): One of the special types of cutaneous leishmaniasis is the Chronic Lupoid Leishmaniasis (CLL), which abnormal immune responses have been implicated in its pathogenesis. On the other hand, HTLV-I infection has been known to be associated with some infectious disease. Human T cell lymphotropic virus type I (HTLV-I) and cutaneous leishmaniasis are endemic in Mashhad, Iran. The objective of this study was to evaluate the frequency of HTLV-I in CLL patients. Materials and Methods: This cross sectional study involved 51 CLL patients admitted to cutaneous leishmaniasis clinics of Ghaem and Imam Reza Hospitals in Mashhad, Iran. The blood samples were examined for HTLV-I by ELISA method. Results: The results of the tests for HTLV-I in all cases were negative. Conclusion: The results of this study showed that there was not significant association between HTLV-I and CLL.
Keywords :
Cutaneous leishmaniasis , Chronic lupoid leishmaniasis , Human T cell lymphotropic virus , type I
Journal title :
Astroparticle Physics
