Author/Authors :
Kishor Prasad, Kaushal Department of Superspeciality of Gastroenterology - Post Graduate Institute of Medical Education and Research, Chandigarh India , K. Sharma, Arun Department of Superspeciality of Gastroenterology - Post Graduate Institute of Medical Education and Research, Chandigarh India , K. Nain, Chander Department of Superspeciality of Gastroenterology - Post Graduate Institute of Medical Education and Research, Chandigarh India , Singh, Kartar Department of Superspeciality of Gastroenterology - Post Graduate Institute of Medical Education and Research, Chandigarh India
Abstract :
Celiac disease (CD) is an autoimmune disorder characterized
by small intestinal mucosal injury and nutrient malabsorption
that affects patients with a specific genetic predisposition (HLA
DR3-DQ2 and HLA DR4-DQ8) who are exposed to gluten, the major
storage protein of wheat and similar grains (1, 2). Abnormal
immune response to gliadin, genetic factors, and environmental
factors play a role in the pathogenesis of CD. Infectious agents
have been implicated in the pathogenesis of many autoimmune
disorders. Transient infections or increased permeability of the
mucosa may facilitate disease onset induced by the uptake of
gluten peptides into a microenvironmental milieu in the small
intestinal mucosa (3).
Keywords :
Viral Hepatitis , Celiac Disease , Autoimmune Diseases , Hepatitis B Virus
