Author/Authors :
Aryana, Kamran Nuclear Medicine Research Center, Mashhad University of Medical Sciences, Mashhad, Iran , Shafiei, Susan Nuclear Medicine Research Center, Mashhad University of Medical Sciences, Mashhad, Iran , Ghahremani, Somayeh Nuclear Medicine Research Center, Mashhad University of Medical Sciences, Mashhad, Iran , Ghahremani, Sarah Pediatrics Department, Imam Reza hospital, Mashhad University of Medical Sciences, Mashhad, Iran , Sabour, Mahsa Nuclear Medicine Research Center, Mashhad University of Medical Sciences, Mashhad, Iran
Abstract :
A 10-year-old boy was referred to us for evaluation of FUO accompanied with bone pain in both calves. Three hours after
intravenous injection of 13 mCi of 99mTc-MDP, whole body scan in multiple spot views was performed. The scan showed
symmetrical areas of diffusely increased tracer uptake in multiple long bones. Histopathologic evaluation confirmed osteosclrosis
and fibrotic changes without any bacterial growth in the specimen culture. Based on patient’s history, lab results, bone scan and
histopathologic findings, chronic recurrent multifocal osteomyelitis (CRMO) was considered as the most likely diagnosis. Dramatic
response to NSAIDs and pamidronate therapy confirmed the diagnosis of CRMO.
Keywords :
Chronic recurrent multifocal osteomyelitis , Bone scintigraphy , Bone scintigraphy , 99mTc-MDP
