Comparison of Interleukin-1β Levels in Gingival Crevicular Fluid and Peri-Implant Crevicular Fluid and Its Relationship with Clinical Indexes

Objective: Interleukin-1ß (IL-1B ) is one of the most important cytokines which seems to have an important role in the inflammatory process in gingival and periimplant tissues. The aim of this split-mouth study was to investigate the relationship between the concentration of IL-1B in gingival crevicular fluid (GCF) and peri-implant crevicular fluid (PICF) and clinical parameters such as plaque index (PI), gingival index (GI), pocket depth (PD) and bone loss (BL). Materials and Methods: In 32 patients, PICF and GCF samples of 41 implants and 41 contralateral teeth were collected and IL-1ß was determined by enzymelinked immunosorbent assay (ELISA). PI, GI, PD and BL were recorded for each of the samples. Result : The positive correlation between the level of IL-1ß and PI, GI, PD and BL in both groups was observed (P<0.0001)