Author/Authors :
Akbarzadeh, Marzieh Community Based Psychiatric Care Research Center - Department of Midwifery - Fatemeh (P.B.U.H) School of Nursing and Midwifery - Shiraz University of Medical Sciences, Shiraz, Iran , Zeinalzadeh, Sanaz Department of Midwifery - School of Nursing and Midwifery - Shiraz University of Medical Sciences, Shiraz, Iran , Zolghadri, Jaleh Department of Obstetrics and Gynecology - School of Medicine - Shiraz University of Medical Sciences, Shiraz, Iran , Mohagheghzadeh, Abdolali Department of Traditional Pharmacy - School of Pharmacy - Shiraz University of Medical Sciences, Shiraz, Iran , Faridi, Pouya Department of Traditional Pharmacy - School of Pharmacy - Shiraz University of Medical Sciences, Shiraz, Iran , Sayadi, Mehrab Department of Bio-statistics - Shiraz University of Medical Sciences, Shiraz, Iran
Abstract :
Background: Orgasmic disorder can create a feeling of deprivation and failure and provide
mental problems, incompatibility and marital discord. This study aimed to compare the effects
of Elaeagnus angustifolia flower extract and sildenafil citrate on female orgasmic disorder
in women in 2013.
Methods: In this randomized clinical trial, 125 women between 18-40 years old who
suffered from orgasmic disorder were divided into three E. angustifolia, sildenafil
citrate and control groups. The data were gathered using Female Sexual Function Index
and through measurement of TSH and prolactin. The first intervention group had
to consume 4.5 gr E. angustifolia extract in two divided doses for 35 days and the
second one had to use 50 mg sildenafil citrate tablets for 4 weeks one hour before
their sexual relationship. However, the control group had to consume the placebo.
The data were analyzed using paired t-test, one-way ANOVA, and Bonferroni posthoc
test and p<0.05 was considered significant.
Results: The frequency of orgasmic disorder before the intervention was 41.5%,
40.5%, and 57.1% in E. angustifolia, sildenafil citrate, and control groups, respectively
(p=0.23). However, these measures were respectively 29.3%, 16.7%, and 50%
after the intervention (p=0.004). A significant difference between the two groups regarding
sexual satisfaction after the intervention (p=0.003) compared to the beginning
of the study (p=0.356). Besides, the highest reduction of changes after the intervention
(58.82%) was observed in the sildenafil citrate group.
Conclusion: Both E. angustifolia extract and sildenafil citrate were effective in reduction
of the frequency of orgasmic disorder in women.
