Author/Authors :
Kasia, Jean Marie Department of Obstetrics and Gynaecology - Faculty of Medicine and Biomedical Sciences - University of Yaoundé I, Yaoundé, Cameroon , Ngowa, Jean Dupont Kemfang Gynecological Endoscopic Surgery and Human Reproductive Teaching Hospital, Yaoundé, Cameroon , Yolande Salome Mimboe Department of Obstetrics and Gynaecology - Faculty of Medicine and Biomedical Sciences - University of Yaoundé I, Yaoundé, Cameroon , Toukam, Michel Laboratory of Clinical Biology - Gynecological Endoscopic Surgery and Human Reproductive Teaching Hospital, Yaoundé, Cameroon , Ngassam, Anny Gynecological Endoscopic Surgery and Human Reproductive Teaching Hospital, Yaoundé, Cameroon , Noa, Claude Cyrile Department of Obstetrics and Gynaecology - Faculty of Medicine and Biomedical Sciences - University of Yaoundé I, Yaoundé, Cameroon , Belinga, Etienne Department of Obstetrics and Gynaecology - Faculty of Medicine and Biomedical Sciences - University of Yaoundé I, Yaoundé, Cameroon , Medou, Alexis Anesthesia Unit - Gynecological Endoscopic Surgery and Human Reproductive Teaching Hospital, Yaoundé, Cameroon
Abstract :
Background: More than 70 million couples suffer from infertility worldwide. The
aim of this study was to evaluate the fertility outcomes after laparoscopic fimbrioplasty
and neosalpingostomy in female infertility.
Methods: Laparoscopic distal tuboplasty was carried out for 402 cases at the Gynecological
Endoscopic Surgery and Human Reproductive Teaching Hospital in Yaoundé-
Cameroon in Central Africa from December 2002 to December 2007. Laparoscopic
fimbrioplasty and neosalpingostomy were done using bipolar electrocoagulation
and conventional endoscopic instruments. Log-rank test was used to compare
cumulative rate curves of intrauterine pregnancy with respect to the tubal stages.
P<0.05 was considered statistically significant.
Results: The mean age of the patients was 31.6±5.45 years. Secondary infertility
was the most frequent type of infertility (70.14%). The laparoscopic tubal surgery
done consisted of fimbrioplasty in 185(46%) cases and neosalpingostomy in 217
(54%) cases. Of 260 women followed up after tuboplasty, there were overall 74
(28.48%) pregnancies; 68(26.1%) intrauterine pregnancies and 6(2.3%) ectopic pregnancies.
Pregnancy rates were significantly associated to the tubal stage (63% in
stage 1, 15% in stage 3 and 00% in stage 4; p<0.001) and the adnexal adhesion
scores (73.91% in the absence of adnexal adhesions and 8.8% in the case of a severe
adnexal adhesion score). Of the 68 intrauterine pregnancies, there were 60(88%) live
births and 8(12%) spontaneous abortions.
Conclusion: It is believed that laparoscopic fimbrioplasty and neosalpingostomy
should be the preferred choice when faced with tubal distal occlusion in a context of
female infertility. This implies that training in endoscopic surgery should be regarded
as an important issue in developing countries.
Keywords :
Adnexal adhesion , Fimbrioplasty , Infertility , Laparoscopy , Neosalpingostomy , Tubal stage