Title of article :
Ovarian Malignant Mixed Germ Cell Tumor: A Case of Unusual Presentation as Molar Pregnancy
Author/Authors :
Aminimoghaddam, Soheila Gynecology Oncology Department - Iran University of Medical Sciences, Tehran, Iran , Mohseni, Iman Gynecology Oncology Department - Iran University of Medical Sciences, Tehran, Iran , Afzalzadeh, Azadeh Gynecology Oncology Department - Iran University of Medical Sciences, Tehran, Iran , Esmaeeli, Shooka Gynecology Oncology Department - Iran University of Medical Sciences, Tehran, Iran
Abstract :
Background: This research was conducted to introduce a patient with rare ovarian
mixed germ cell tumor, presented as molar pregnancy.
Case Presentation: The patient was a 16 year old woman admitted with diagnosis of
molar pregnancy. Abdominal enlargement was the only complaint. She had a large
pelvic mass in physical examination. The first diagnosis was molar pregnancy due to
previous ultrasonic reports and positive βeta HCG. Urine pregnancy test was positive.
As suction curettage was performed for her, surprisingly, the size of uterus was
normal and no molar tissue was found in pathologic examination. At intraoperative
ultrasound exam, an extra-uterine heterogeneous mass was found. Extra-uterine
mass was confirmed by CT and MRI done after suction curettage. Mixed germ cell
tumor was confirmed by histological examination after laparatomy and removing
tumoral mass. Finally, she received Bleomycin, Etoposide and Cisplatin (BEP) regimen
in four courses and Vincristine, Actinomycin D (Dactinomycin) and Cyclophosphamide
(VAC) regimen in two courses and Diphereline for saving the other
ovary.
Conclusion: Some young patients misinterpret the early symptoms of an ovarian neoplasm
as those of pregnancy which can lead to a delay in the diagnosis.
Keywords :
BEP , Embryonal carcinoma , Germ cell tumor , Molar pregnancy , Tumor marker , VAC , Yolk sac tumor
Journal title :
Astroparticle Physics