Author/Authors :
Al-Zoubi, Mazhar Salim Deparrment - Yarmouk University - Irbid, Jordan , Al-Tayyar, Ibrahim Ali Department of Medical Laboratory Science - Faculty of Engineering & Technology - Brack - Sebha University, Lybia , Hussein, Emad Deparrment - Yarmouk University - Irbid, Jordan , Al Jabali, Alla Deparrment - Yarmouk University - Irbid, Jordan , Khudairat, Salih
Abstract :
Background and Objectives: The global spread of methicillin resistant Staphylococcus aureus (MRSA) constitutes one of
the most serious contemporary challenges to the treatment of hospital-acquired infections. We aimed to screen and assess
the antibiotic susceptibility pattern of Staphylococcus aureus isolated from clinical specimens in local hospitals of Northern
province in Jordan.
Materials and Methods: Staphylococcus aureus was isolated and identified using standard methods from various clinical
specimens of different infected body sites from 358 patients during the period from January 2008 to November 2012.
Results: Our analysis showed that 31.6% of S. aureus infections were MRSA, while 31% were multidrug resistance (MDR)
and 42.7% were Oxacillin-resistant (ORSA). Most of these strains were isolated from wound specimens. All isolates were
susceptible to vancomycin (100%). They were also susceptible to chloramphenicol, linezolid, nitrofurantoin, rifampicin and
teicoplanin (>80%), but showed resistance to erythromycin and penicillin.
Conclusion: Vancomycin was the most effective antimicrobial agent against S. aureus. We recommend regular surveillance
of hospital associated infections and monitoring antibiotic sensitivity pattern and strict drug policy for antibiotics used within
and outside the hospital environments.
