Comment on: Pomegranate Flower Extract Does Not Prevent Cisplatin‑induced Nephrotoxicity in Female Rats

DEAR EDITOR, We read with interest the recently published letter which was commented on an article previously published in the “International Journal Prevention Medicine” by Jilanchi et al., entitled “Pomegranate flower extract does not prevent cisplatin?induced nephrotoxicity in female rats.” The author of the commentary letter has pointed to the results of Jilanchi et al. and concluded that phytoestrogens are the cause of aggravation or negative results response of pomegranate flower extract (PFE) on nephrotoxicity induced by cisplatin (CP) in female rats. Here, we would like to discuss the results of the main paper and explain about the commentary letter written on the results of this article.