Title of article :
Synthesis of thiadiazine-3,7-diamine derivatives
Author/Authors :
razzaghi asl, Nima Department of pharmaceutical chemistry - ardabil university of medical sciences, ardabil, iran , Mohammadi, Mohammad Kazem Factually of Science - Ahvaz Branch Islamic Azad University, Ahvaz, Iran
Abstract :
Abstract- New 1,5-tetra alkyl methyl- phenyl-1H-pyrimido[4,5-e][1,3,4]thiadiazine-3,7-diamine were synthesized via the cyclocondensation of 2-(5-bromo-2-chloro-6-methylpyrimidin-4-yl)-2-methylhydrazine with phenylthioisothiocyanate and further replacement of chlorine atom on the seven number position of pyrimido[4, 5- e][1, 3, 4]thiadiazin by appropriate secondary amines in simple and efficient methods.
Keywords :
phenylthioisothiocyanate , 2-(5-bromo-2-chloro-6-methylpyrimidin-4-yl)-2-methylhydrazine , 5- bromo- 2,4- dichloro-6- methylpyrimidine , heterocyclization
Journal title :
Astroparticle Physics
