Title of article
Screen-printed Electrode Modified with Magnetic Core-shell Nanoparticles for Detection of Chlorpromazine
Author/Authors
Mohammadi, Zia Department of Chemistry - Payame Noor University - Tehran , Sarhadi, Amir Hossein Department of Chemistry - Payame Noor University - Tehran , Mosazadeh, Farideh School of Public Health - Bam University of Medical Sciences - Bam
Pages
10
From page
1
To page
10
Abstract
In the present study, magnetic core-shell manganese ferrite nanoparticles (MCMNP) were synthesized and used for construction of a magnetic core-shell manganese ferrite nanoparticles modified screen-printed carbon electrode (MCSNP-SPCE). Cyclic voltammetry was used to study the electrochemical behavior of chlorpromazine (CPZ) and its determination was conducted by applying square wave voltammetry (SWV). The MCSNP-SPCE in comparison with bare SPCE exhibited enhanced electrocatalytic activity toward the oxidation of CPZ. A single irreversible oxidation peak was observed at a potential of 500 mV and 630 mV on the MCSNP-SPCE and bare SPCE, respectively. Under the optimized conditions, the anodic peak current of CPZ recorded by SWV varies linearly with CPZ concentration in the range 0.25-60 μM with a detection limit of 0.08 μM. The MCSNP-SPCE was used for quantitative analysis of CPZ in tablet and urine
samples and the results indicate the feasibility of the amperometric method for CPZ analysis in routine detection.
Keywords
Screen-printed carbon electrode , Magnetic core shell nanoparticles , Chlorpromazine determination
Journal title
Astroparticle Physics
Serial Year
2018
Record number
2428399
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