Title of article :
Biginelli Synthesis and Theoritical Study of Dihydropyrimidinones
Author/Authors :
Farjam, Mohammad Hosein Department of Chemistry - Firoozabad Branch Islamic Azad University, Firoozabad, Iran , Rezaei, Ramin Department of Chemistry - Firoozabad Branch Islamic Azad University, Firoozabad, Iran
Abstract :
An effective one-pot synthesis of dihydropyrimidinonoes in solvent free conditions using CuCl2 as an inexpensive and readily available reagent through Biginelli condensation reaction of aldehyde derivatives, 1,3-dicarbonyl compounds and urea is described. Excellent yields, short reaction times for formation of the products and simple work-up are attractive features of this green protocol.
Keywords :
Solvent-free , One-pot , Dihydropyrimidinones , Biginelli reaction
Journal title :
Astroparticle Physics
