Author/Authors :
Shariati, Behnam Department of Psychiatry - Rasoul-e-Akram Hospital - Iran University of Medical Sciences, Tehran , Shabani, Amir Iran University of Medical Sciences, Tehran , Ariana-Kia, Elmira Department of Clinical Psychology - School of Education and Psychology - Shiraz University, Shiraz , Ahmadzad-Asl, Masoud Iran University of Medical Sciences, Tehran , Alavi, Kaveh Department of Psychiatry - Iran Psychiatric Hospital, Tehran , Mousavi Behbahani, Zohreh Department of Psychiatry - Iran Psychiatric Hospital, Tehran , Ghasemzadeh, Mohammad Reza Department of Psychiatry - AJA University of Medical Sciences, Tehran , Hasani, Sahar Department of Psychiatry - Iran Psychiatric Hospital, Tehran , Ghiasi, Zahra Department of Psychiatry - Zahedan University of Medical Sciences, Zahedan , Kashaninasab, Fatemeh Department of Psychiatry - Rasoul-e-Akram Hospital - Iran University of Medical Sciences, Tehran , Tajik Esmaeeli, Soodeh Department of Psychiatry - Iran Psychiatric Hospital, Tehran , Najjarzadegan, Mohammad Reza Department of Psychiatry - Iran Psychiatric Hospital, Tehran , Kheirolahi, Amin Department of Psychiatry - Iran Psychiatric Hospital, Tehran , Beihaghi, Mahboobeh Department of Psychiatry - Iran Psychiatric Hospital, Tehran , Shariat, Vahid Department of Psychiatry - Iran Psychiatric Hospital, Tehran , Nohesara, Shabnam Department of Psychiatry - Iran Psychiatric Hospital, Tehran
Abstract :
Background: A negative attitude toward treatment is a major obstacle to treat bipolar disorder.
Objectives: The current study aimed at assessing the reliability and validity of Persian version of drug attitude inventory (DAI-10)
in patients with bipolar I disorder and finding its relationship with patients’ compliance in order to predict the disorder.
Methods: To assess test-retest reliability, 30 outpatients with bipolar I disorder were selected. They were asked to answer the questions
at the onset of the study and four to ten days later. Then, the relationship between DAI-10 scores of 82 patients in bipolar
disorder patients’ follow-up (BDPF) study, and medication possession ratio (MPR) were investigated. The patients were divided into
poor and good compliance, and cut off point of the tool was assigned. Positive and negative predictive value of DAI score was also
calculated.
Results: Test-retest reliability was 0.805 and Cronbach’s0.787. Concurrent validity between DAI-10 score and that of theMPRat the
study time was 0.676, and positive predictive value of DAI-10 score for medication compliance at assessment time was about 88.9%.
Predictive validity of DAI-10 score for next six months was about 0.663 and cut off point +1, with the specificity of 81.5% and sensitivity
of 89.1%; the positive predictive value of questionnaire score for medication compliance was 90.7%. The Spearman correlation
coefficient between the two tests was 0.822 (95% confidence interval (CI): 0.652 - 0.901).
Conclusions: DAI-10 is a reliable and valid tool to identify attitude of patients with bipolar disorder type I towards treatment with
medications.
