Title of article :
Gold-Silver Hybrid Nanoparticles as a Novel Carrier for Electrochemical Study of Redox Protein
Author/Authors :
Eskandari, Khadijeh Nanobiotechnology Research Center - Baqiyatallah University of Medical Sciences , Mah-Heidari, Naimeh Nanobiotechnology Research Center - Baqiyatallah University of Medical Sciences , Fasihi-Ramandi, Mahdi Molecular Biology Research Center - Systems Biology and Poisoning Institute - Baqiyatallah University of Medical Sciences , Heiat, Mohammad Applied Biotechnology Research Center - Baqiyatallah University of Medical Sciences , Dashtestani, Fariba Nanobiotechnology Research Center - Baqiyatallah University of Medical Sciences , Kamali, Mehdi Nanobiotechnology Research Center - Baqiyatallah University of Medical Sciences , Ashiani, Danial Nanobiotechnology Research Center - Baqiyatallah University of Medical Sciences
Abstract :
Noble metal nanoparticles have a great potential for biological study, especially the
use of gold nanoparticles is popular. In this work gold nanoparticles (GNPs), silver
nanoparticles (SNPs) and gold-silver hybrid nanoparticles (HNPs) synthesized and
used as a carrier for electrochemical investigation of redox protein. Optical characterization
of these nanoparticles was performed by UV-Vis spectroscopy. The
optical absorption spectra of HNPs solution shows only one plasmon absorption, it
is concluded that mixing of gold and silver leads to a homogeneous formation of
alloy nanoparticles. LCR meter study shows the HNPs is best conductance in compare
of GNPs and SNPs. Therefore, the electron transfer of the homogenous
glucose oxidase (GOx), horse radish peroxides (HRP) and hemoglobin (Hb) was
investigates by electrochemical method in presence of HNPs. They demonstrated
quasi-reversible cyclic voltammograms with a formal potential of -479, -178 and,
168 mV in 50 mM phosphate buffer solution at pH 7.4 respectively.
Keywords :
Gold Nanoparticles , Silver Nanoparticles , Gold-Silver Hybrid Nanoparticles
Journal title :
Astroparticle Physics
