Title of article :
Marine-Lenhart syndrome with papillary thyroid carcinoma
Author/Authors :
Atmaca, Hussite Departments of Endocrinology and Metabolism , Çolak, Ramis Departments of Endocrinology and Metabolism , Yazici, Zihni Acar Ondokuz Mayis University Medical School - Samsun - Department of Microbiology - Recep Tayyip Erdogan University Medical School - Rize, Turkey , Kefeli, Mehmet Ondokuz Mayis University Medical School - Samsun - Department of Microbiology - Recep Tayyip Erdogan University Medical School - Rize, Turkey , Tosun, Fevziye Canbaz Ondokuz Mayis University Medical School - Samsun - Department of Microbiology - Recep Tayyip Erdogan University Medical School - Rize, Turkey
Abstract :
Graves’ disease with accompanying functioning nodules is known as Marine-Lenhart syndrome. Autonomously functioning thyroid
nodules (AFTNs) also within Graves’ thyroid tissue are almost always bening in nature. A 45-year-old man developed hyperthyroidism
due to the coexistence of Graves’ disease and AFTN. Total thyroidectomy was performed. The hyperfunctioning nodule with centrally
hypoactive foci detected by technetium-99m thyroid scanning was histologically diagnosed as papillary thyroid carcinoma that was
2.5 cm in diameter. We report the presence of papillary thyroid carcinoma within AFTN in patients with Marine-Lenhart syndrome,
which has not been reported so far.
Keywords :
toxic nodular goitre , Marine-Lenhart syndrome , Autonomously functioning thyroid nodule , Graves’ disease, hyperthyroidism , papillary microcarcinoma , papillary thyroid carcinom , thyroid scintigraphy
Journal title :
Astroparticle Physics
