Author/Authors :
Olang, Beheshteh Department of Pediatric Gastroentrology and Hepatology - Mofid Children’s Hospital - Shahid Beheshti University of Medical Sciences, Tehran , Imanzadeh, Farid Department of Pediatric Gastroentrology and Hepatology - Mofid Children’s Hospital - Shahid Beheshti University of Medical Sciences, Tehran , Nasri, Peiman Department of Pediatric Gastroentrology and Hepatology - Mofid Children’s Hospital - Shahid Beheshti University of Medical Sciences, Tehran , Sayyari, Aliakbar Department of Pediatric Gastroentrology and Hepatology - Mofid Children’s Hospital - Shahid Beheshti University of Medical Sciences, Tehran , Dara, Naghi Department of Pediatric Gastroentrology and Hepatology - Mofid Children’s Hospital - Shahid Beheshti University of Medical Sciences, Tehran , Khatami, Katayoon Department of Pediatric Gastroentrology and Hepatology - Mofid Children’s Hospital - Shahid Beheshti University of Medical Sciences, Tehran , Rouhani, Pejman Department of Pediatric Gastroentrology and Hepatology - Mofid Children’s Hospital - Shahid Beheshti University of Medical Sciences, Tehran , Sadeghi, Somayeh Department of Internal Medicine - Al-Zahra Hospital - Isfahan University of Medical Sciences, Isfahan , Abdollah, Karimi Shahid Beheshti University of Medical Sciences , Nilipoor, Yalda Shahid Beheshti University of Medical Sciences , Mansuri, Mahbubeh Shahid Beheshti University of Medical Sciences
Abstract :
Background: Evidence has shown a link between allergic disease and inflammatory bowel diseases (IBDs). We investigated food allergy
in Iranian pediatric IBD patients. Materials and Methods: A cross-sectional study was conducted on a consecutive sample of children
with newly diagnosed IBD referring to Mofid Children’s University Hospital in Tehran (Iran) between November 2013 and March 2015.
Data on age, gender, history of cow’s milk allergy (CMA), IBD type, routine laboratory tests, and colonoscopic and histopathological
findings were gathered. Food allergy was assessed with the skin prick test (SPT). Results: A total of 28 patients including 19 ulcerative
colitis (UC), 7 Cronh’s disease (CD), and two with unclassified colitis with a mean age of 8.3 ± 4.4 years. (57.1% females, 42.9% were
studied. History of CMA was present in eight patients (28.6%). Seventeen patients (60.7%) had at least one food allergy (68.4% of UC
vs. 42.9% of CD, P = 0.230). Ten patients (35.7%) had multiple food allergies (36.8% of UC vs. 42.9% of CD, P > 0.999). Common allergic
foods were cow’s milk (28.6%), beef, seafood, albumen, wheat, and walnuts (each 10.7%), and peanuts and chestnuts (each 7.1%). The SPT
showed CMA in 68.4% (8/17) of UC but none of the CD patients (P = 0.077). Conclusion: Food allergy is frequent in Iranian pediatric
IBD patients with CMA being the most common observed allergy. The CMA seems to be more frequent in UC than in CD patients.
Keywords :
ulcerative colitis , inflammatory bowel diseases , food hypersensitivity , Crohn’s disease
