Title of article :
Burden of ischemic heart diseases in Iran, 1990-2010: Findings from the Global Burden of Disease study 2010
Author/Authors :
Maracy, Mohammad Reza Department of Biostatistics and Epidemiology - School of Public Health - Isfahan University of Medical Sciences , Isfahani, Motahareh Tabar Department of Biostatistics and Epidemiology - School of Public Health - Isfahan University of Medical Sciences , Kelishadi, Roya Department of Pediatrics - Child Growth and Development Research Center - Research Institute for Primordial Prevention of Non-communicable Disease - Isfahan University of Medical Sciences, Isfahan , Ghasemian, Anoosheh Non-communicable Diseases Research Center - Endocrinology and Metabolism Population Sciences Institute - Tehran University of Medical Sciences , Djalalinia, Shirin Non-communicable Diseases Research Center - Endocrinology and Metabolism Population Sciences Institute - Tehran University of Medical Sciences , Majidi, Somayye Non-communicable Diseases Research Center - Endocrinology and Metabolism Population Sciences Institute - Tehran University of Medical Sciences , Qorbani, Mostafa Non-communicable Diseases Research Center - Endocrinology and Metabolism Population Sciences Institute - Tehran University of Medical Sciences , Sharifi, Farshad Elderly Health Research Center - Endocrinology and Metabolism Population Sciences Institute - Tehran University of Medical Sciences , Shabani, Reihaneh Department of Cardiology - Shahid Rajaei Hospital - Iran University of Medical Sciences , Ansari, Hossein Department of Epidemiology and Biostatistics - Health Promotion Research Center - Zahedan University of Medical Sciences, Zahedan , Asayesh, Hamid Department of Medical Emergencies - Qom University of Medical Sciences, Qom
Abstract :
Background: Cardiovascular diseases are viewed worldwide as one of the main causes of death.This study aims to report
the burden of ischemic heart diseases (IHDs) in Iran by using data of the global burden of disease (GBD) study, 1990-2010.
Materials and Methods: The GBD study 2010 was a systematic effort to provide comprehensive data to calculate disability-adjusted
life years (DALYs) for diseases and injuries in the world. Years of life lost (YLLs) due to premature mortality were computed on the
basis of cause-of-death estimates, using Cause of Death Ensemble model (CODEm). Years lived with disability (YLDs) were assessed
by the multiplication of prevalence, the disability weight for a sequel, and the duration of symptoms. A systematic review of published
and unpublished data was performed to evaluate the distribution of diseases, and consequently prevalence estimates were calculated
with a Bayesian meta-regression method (DisMod-MR). Data from population-based surveys were used for producing disability
weights. Uncertainty from all inputs into the calculations of DALYs was disseminated by Monte Carlo simulation techniques.
Results: The age-standardized IHDs DALY specified rate decreased 31.25% over 20 years from 1990 to 2010 [from 4720 (95%
uncertainty interval (UI): 4,341-5,099) to 3,245 (95% UI: 2,810-3,529) person-years per 100,000]. The decrease were 38.14% among
women and 26.87% among men. The age-standardized IHDs death specefied rate decreased by 21.17% [from 222) 95% UI: 207-243
(to 175 (95% UI:152-190) person-years per 100,000] in both the sexes. The age-standardized YLL and YLD rates decreased 32.05%
and 4.28%, respectively, in the above period. Conclusion: Despite decreasing age-standardized IHD of mortality, YLL, YLD, and
DALY rates from 1990 to 2010, population growth and aging increased the global burden of IHD. YLL has decreased more than IHD
deaths and YLD since 1990 but IHD mortality remains the greatest contributor to disease burden.
Keywords :
years lived with disability (YLDs) , ischemic heart diseases (IHDs) , disability-adjusted life years (DALYs) , Burden of disease Iran
Journal title :
Astroparticle Physics
