Idiopathic Retinal Vasculitis, Aneurysm, Neuroretinitis: A Significant Increase in Visual Acuity after Treatment with One Session of Panretinal Photocoagulation, Retinopexy and Three Consecutive Intravitreal Bevacizumab (Avastin) Injection

Purpose: To report an idiopathic retinal vasculitis, aneurysm, neuroretinitis (IRVAN) case treated with one session of panretinal photocoagulation (PRP) and intravitreal bevacizumab (Avastin) Case report: A 13-year-old boy was diagnosed as an IRVAN syndrome. Systemic examination, fundus angiography, brain MRI were performed to evaluate the patient. Treatment with one session of PRP, retinopexy and 3 consecutive monthly intravitreal injection of 1.25 mg Bevacizumab was performed. After the second Bevacizumab injection, complete regression of neovascularizations and improvement of visual acuity (VA) to 3/10 for right eye and 6/10 for left eye was noted. By the other 2 additional monthly intravitreal injection of Bevacizumab, VA improved to 6/10 and 8/10 for right and left eye. The Aneurysms became smaller. After 6 months of his treatment, his VA was remained stable. Conclusion: We reported a successful treatment effect of Bevacizumab as an adjunctive therapy in combination with PRP and retinopexy, for stage 3 IRVAN. Bevacizumab seems to have promising effects in the treatment of IRVAN.