Author/Authors :
Soltani Moghadam, Reza Department of Ophthalmology - Guilan University of Medical Sciences, Tehran , Hashemian, Mohammad Nasser Eye Research Center - Farabi Eye Hospital - Tehran University of Medical Sciences, Tehran , Rahimi, Firoozeh Eye Research Center - Farabi Eye Hospital - Tehran University of Medical Sciences, Tehran , Alipour, Fatemeh Eye Research Center - Farabi Eye Hospital - Tehran University of Medical Sciences, Tehran , Ahmadraji, Ali Asghar Eye Research Center - Farabi Eye Hospital - Tehran University of Medical Sciences, Tehran , Torabi, Hamid Reza Eye Research Center - Farabi Eye Hospital - Tehran University of Medical Sciences, Tehran , Tavakoli, Niloofar Resident in Nuclear Medicine - Nuclear Medicine Research Center - Shariati Hospital - Tehran University of Medical Sciences, Tehran
Abstract :
Purpose: To evaluate the effect of topical diclofenac sodium 0.1% on the corneal epithelial healing
after photorefractive keratectomy (PRK)
Methods: In this prospective randomized double blind clinical trial, PRK was performed on 82
patients. Thirty-three cases of them receiving topical diclofenac four times per day after surgical
procedure and 45 patients did not receive this medication as a control group. Patients were
compared for corneal epithelial healing after treatment.
Results: Statistically significant delayed epithelial healing has been found in the treatment group 24
hours after PRK but corneal reepithelialization has been completed in all patients four days after
surgery.
Conclusion: Postoperative topical diclofenac used following PRK may delay the epithelial healing.
