Title of article :
The epidemiology of microbial agents related to patients with multiple sclerosis (MS
Author/Authors :
Navidinia, Masoumeh School of Allied Medical Sciences - Shahid Beheshti University of Medical Sciences, Tehran , Gholinejad, Khadijeh School of Allied Medical Sciences - Shahid Beheshti University of Medical Sciences, Tehran , Derakhshan, Safoura Department of Microbiology - Faculty of Medicine - Kurdistan University of Medical Sciences, Sanandaj , Rahimipour, Ali School of Allied Medical Sciences - Shahid Beheshti University of Medical Sciences, Tehran , Kazerouni, Faranak School of Allied Medical Sciences - Shahid Beheshti University of Medical Sciences, Tehran , Sahraian, Mohammad Ali Tehran University of Medical Sciences, Tehran
Abstract :
Multiple Sclerosis (MS) is one of the autoimmune diseases which affects the central nervous system
and its etiology has not yet been identified. The disparity between youth and disability in reproductive
ages is considered to be of particular importance for this disease and the need for research which
illuminates various epidemiological, etiologic, clinical and therapeutic angles of multiple sclerosis is
deeply felt. The purpose of this study is to consider the epidemiology of microbial agents related to
patients with multiple sclerosis (MS). From 37 patients with multiple sclerosis according to the
physician examination and McDonald criteria , serum samples were taken. Until testing, serum samples
were stored in a freezer at -70 ° C. Subsequently, viral and bacterial agents were identified using
specific primers and PCR method. In this study, the numbers of microbial agents were as the following:
7 retrovirus associated with MS (MRSV), 17 EBV, 8 HSV6, 11 JC virus, 10 CMV, 8 B19, 14Corona
virus, 1 Helicobacter pylori, 15 Acinetobacter, 9 Borrelia burgdorferi, and 19 Chlamydia pneumonia.
Identification of the relationship between different infectious agents in MS is necessary to prepare
feasible data about tracing and treatment of MS related to these microorganisms that may be beneficial
to clinicians to select a convenient empirical therapeutic diet in MS related to pathogens at the bedhead
and can open up a new path to new therapeutic approaches.
Keywords :
Multiple Sclerosis patients , Microbial Agents , PCR
Journal title :
Astroparticle Physics