Title of article :
Microwave-assisted green approach toward the unexpected synthesis of pyrazole-4-carboxylates
Author/Authors :
Arshia H. E. J. Research Institute of Chemistry - International Centre for Chemical and Biological Sciences - University of Karachi - Karachi - Pakistan , Saad, muhammad H. E. J. Research Institute of Chemistry - International Centre for Chemical and Biological Sciences - University of Karachi - Karachi - Pakistan , Mohammed khan, Khalid H. E. J. Research Institute of Chemistry - International Centre for Chemical and Biological Sciences - University of Karachi - Karachi - Pakistan , Pervin, shahnaz PCSIR Laboratories Complex -Karachi - Pakistan , Voelter, Wolfgang Interfakultäres Institut für Biochemie - Universität Tübingen - Tübingen - Germany
Abstract :
A practically efficient, environment friendly, and solvent free microwave-assisted protocol was developed for the synthesis of pyrazole-4-carboxylates. In this connection, we synthesized five new compounds (4a-4e) via microwave irradiation of a mixture of benzophenone hydrazones and acetoacetates in the absence of solvent. Short reaction time, easy workup and quantitative yield are the striking features of our protocol.
Keywords :
Microwave-assisted organic synthesis , Green chemistry , Solvent free , Pyrazole
Journal title :
Astroparticle Physics
