Title of article :
Endogenous Nocardial Endophthalmitis in an Immunosuppressed Patient: A Serious Warning of an Underlying Life Threatening and Blinding Disorder
Author/Authors :
Trehan, Hemant Department of Ophthalmology - Army Hospital Research and Referral - Delhi Cantonment, India , Kaushik, Jaya Department of Ophthalmology - Army Hospital Research and Referral - Delhi Cantonment, India , Jain, Vaibhav Kumar Department of Ophthalmology - Uttar Pradesh Rural Institute of Medical Sciences - Saifai - Etawah - Uttar Pradesh, India , Parihar, Jitendra Kumar Singh Department of Ophthalmology - Army Hospital Research and Referral - Delhi Cantonment, India , Avasthi, Abhijit Department of Ophthalmology - Army Hospital Research and Referral - Delhi Cantonment, India
Abstract :
Purpose: To report a case of bilateral endogenous nocardial endophthalmitis with central nervous system
involvement in an immunocompromised individual with an extremely poor outcome.
Case Report: A 35‑year‑old man with a history of long‑term, prescribed oral steroid use for
membranoproliferative glomerulonephritis presented with profound bilateral vision loss. Patient’s diagnosis
of bilateral endogenous nocardial endophthalmitis was delayed. Nocardia was finally isolated from a brain
biopsy after a repeat magnetic resonance imaging revealed a brain abscess. With anti‑nocardia therapy,
patient improved systemically, but the visual outcome was poor, with no light perception in both eyes.
Conclusion: Ocular nocardiosis is a serious vision and life threatening disorder, particularly in patients on
immunosuppressive therapy. A high index of suspicion is required for successful treatment.
Keywords :
Ahmed Glaucoma Valve , Bilateral Endogenous Nocardial Endophthalmitis , Brain Abscess , Glomerulonephritis , Membranoproliferative Glomerulonephritis , Ocular Nocardiosis
Journal title :
Astroparticle Physics
