Author/Authors :
Faghihi, Hooshang Noor Ophthalmology Research Center - Noor Eye Hospital, Tehran, Iran , Hajizadeh, Fedra Noor Ophthalmology Research Center - Noor Eye Hospital, Tehran, Iran , Hashemi, Hassan Noor Ophthalmology Research Center - Noor Eye Hospital, Tehran, Iran , Khabazkhoob, Mehdi Dezful University of Medical Sciences, Dezful, Iran
Abstract :
Purpose: To determine the agreement between Spectralis and Cirrus spectral domain
optical coherence tomography (SD-OCT) measurements of peripapillary retinal nerve
fiber layer (RNFL) thickness.
Methods: Suspected or confirmed cases of glaucoma who met the inclusion criteria
underwent peripapillary RNFL thickness measurement using both the Spectralis and
Cirrus on the same day within a few minutes.
Results: Measurements were performed on 103 eyes of 103 patients with mean age of
50.4±17.7 years. Mean RNFL thickness was 89.22±15.87 versus 84.54±13.68 μm using Spectralis and Cirrus, respectively. The difference between measurements and the average of paired measurements with the two devices showed a significant linear
relationship. Bland-Altman plots demonstrated that Spectralis thickness values were
systematically larger than that of Cirrus.
Conclusion: Spectralis OCT generates higher peripapillary RNFL thickness readings
as compared to Cirrus OCT; this should be kept in mind when values obtained with
different instruments are compared during follow-up.
