Targeted Screening for Predominant CYP1B1 Mutations in Primary Congenital Glaucoma

Advances in molecular genetic techniques and their application to various clinical entities have provided major improvements in prenatal, pre‑symptomatic and preclinical diagnosis of human medical conditions. Further investigations are underway to develop faster, better and less costly diagnostic techniques that can be easily implemented in everyday clinical settings. However, all such clinical studies and technical improvements require extensive initial investigation of the clinical entities for a given targeted population and development of a simple molecular test that can easily be implemented in laboratories with limited access to modern and expensive testing equipment.