Author/Authors :
Saedisomeolia, Ahmad Department of Nutrition and Biochemistry - School of Public Health - Tehran University of Medical Sciences, Tehran , Djalali, Mahmoud Department of Nutrition and Biochemistry - School of Public Health - Tehran University of Medical Sciences, Tehran , Malekshahi Moghadam, Ali Faculty of Veterinary Medicine - The University of Tehran, Tehran , Ramezankhani, Ozra Department of Nutrition and Biochemistry - School of Public Health - Tehran University of Medical Sciences, Tehran , Najmi, Laya Department of Nutrition and Biochemistry - School of Public Health - Tehran University of Medical Sciences, Tehran
Abstract :
BACKGROUND: This study aimed to determine red blood cell (RBC) and serum folate and vitamin B12 levels as well as
their intake in schizophrenic patients.
METHODS: The folate and cobalamin status of 60 schizophrenic patients (15-55 years) was compared to 60 matched
healthy controls using Radio Isotope Dilution Assay (RIDA).
RESULTS: Serum and RBC folate in schizophrenic patients was significantly lower than the control group. Mean serum
cobalamin levels in the schizophrenic group were higher than controls.
CONCLUSIONS: This study showed that folate deficiency is common in schizophrenic patients; therefore, it is important
to pay attention to folate levels in these patients.
Keywords :
Folic Acid , Vitamin B12 , Schizophrenia , Eating