Comment on: The effects of Vitamin E and Selenium on cisplatin-induced nephrotoxicity in cancer patients treated with cisplatin-based chemotherapy: A randomized, placebo-controlled study

We read with great interest the published article in the esteemed ‘Journal of Research in Medical Sciences’, by Hemati et al., entitled, “The effects of vitamin E and selenium on cisplatin-induced nephrotoxicity in cancer patients treated with cisplatin-based chemotherapy: A randomized, placebo-controlled study”. In 22 cancerous patients, who received 400 IU vitamin E and 200 μg selenium daily and 24 patients, who received placebo, they found that vitamin E and selenium can be used to reduce cisplatin-induced nephrotoxicity and bone marrow suppression.[1] In this paper, we would like to mention a few points about kidney protective efficacy of selenium.