Author/Authors :
Wang, Hui Department of Central Laboratory - Hospital - Guangxi Key Laboratory of Metabolic Diseases Research - Guilin, Guangxi, R.P. China , Sui, Weiguo Department of Central Laboratory - Hospital - Guangxi Key Laboratory of Metabolic Diseases Research - Guilin, Guangxi, R.P. China , Xue, Wen Department of Central Laboratory - Hospital - Guangxi Key Laboratory of Metabolic Diseases Research - Guilin, Guangxi, R.P. China , Wu, Junyong Department of Central Laboratory - Hospital - Guangxi Key Laboratory of Metabolic Diseases Research - Guilin, Guangxi, R.P. China , Cong, Shan Department of Central Laboratory - Hospital - Guangxi Key Laboratory of Metabolic Diseases Research - Guilin, Guangxi, R.P. China , Chen, Jiejing Department of Central Laboratory - Hospital - Guangxi Key Laboratory of Metabolic Diseases Research - Guilin, Guangxi, R.P. China , Dai, Yong Department of Central Laboratory - Hospital - Guangxi Key Laboratory of Metabolic Diseases Research - Guilin, Guangxi, R.P. China
Abstract :
Systemic lupus erythematosus (SLE) is a prototypical
autoimmune rheumatic disease principally affecting
women during childbearing years. It is the most
heterogeneous autoimmune disease that affects multiple
organs.[1] However, the exact pathogenesis of SLE
remains uncertain, and might be involving numerous
genes which leads to inconsistent findings in genetic
studies. One possibility of failure to replicate some
single-locus results is that the underlying genetics of
SLE is based on multiple genes with minor effects.
Keywords :
Univariation and multiple linear , SLE , Chin , genes and systemic
