Author/Authors :
Saghafi, Fatemeh Department of Clinical Pharmacy and Pharmacy Practice - Faculty of Pharmacy and Pharmaceutical Sciences - Isfahan University of Medical Sciences, Isfahan , Zargarzadeh, Amir H Department of Clinical Pharmacy and Pharmacy Practice - Faculty of Pharmacy and Pharmaceutical Sciences - Isfahan University of Medical Sciences, Isfahan
Abstract :
Background: Increasing number of reports on medication errors and relevant subsequent damages, especially in medical centers has
become a growing concern for patient safety in recent decades. Patient safety and in particular, medication safety is a major concern
and challenge for health care professionals around the world. Our prospective study was designed to detect prescribing, transcribing,
dispensing, and administering medication errors in two major university hospitals. Materials and Methods: After choosing 20 similar
hospital wards in two large teaching hospitals in the city of Isfahan, Iran, the sequence was randomly selected. Diagrams for drug
distribution were drawn by the help of pharmacy directors. Direct observation technique was chosen as the method for detecting
the errors. A total of 50 doses were studied in each ward to detect prescribing, transcribing and administering errors in each ward.
Th e dispensing error was studied on 1000 doses dispensed in each hospital pharmacy. Results: A total of 8162 number of doses of
medications were studied during the four stages, of which 8000 were complete data to be analyzed. 73% of prescribing orders were
incomplete and did not have all six parameters (name, dosage form, dose and measuring unit, administration route, and intervals of
administration). We found 15% transcribing errors. One-third of administration of medications on average was erroneous in both
hospitals. Dispensing errors ranged between 1.4% and 2.2%. Conclusion: Although prescribing and administrating compromise
most of the medication errors, improvements are needed in all four stages with regard to medication errors. Clear guidelines must
be written and executed in both hospitals to reduce the incidence of medication errors.
Keywords :
Disguised direct observation , hospital , inpatient , medication error