Author/Authors :
Shams, Fatemeh School of Medicine - Montaserie Organ Transplantation Hospital - Mashhad University of Medical Sciences, Mashhad , Shaarbaf Eidgahi, Elham School of Medicine - Montaserie Organ Transplantation Hospital - Mashhad University of Medical Sciences, Mashhad , Lotfi, Zahra School of Medicine - Montaserie Organ Transplantation Hospital - Mashhad University of Medical Sciences, Mashhad , Khaledi, Azad Department of Microbiology and Virology - Antimicrobial Resistance Research Center - Faculty of Medicine - Mashhad University of Medical Sciences, Mashhad , Shakeri, Sepideh Department of Hematology and Blood Bank - Cancer Molecular Pathology Research Center - Faculty of Medicine - Mashhad University of Medical Sciences, Mashhad , Sheikhi, Maryam Department of Hematology and Blood Bank - Cancer Molecular Pathology Research Center - Faculty of Medicine - Mashhad University of Medical Sciences, Mashhad , Bahrami, Afsane School of Medicine - Montaserie Organ Transplantation Hospital - Mashhad University of Medical Sciences, Mashhad
Abstract :
Background: One of the main causes of adverse complications following kidney transplantation is urinary tract infection (UTI). This
study was done to define the incidence rate, clinical profiles, causative microorganisms, and UTI risk factors among kidney transplant
recipients in Mashhad city. Materials and Methods: In this retrospective study, we perused medical files of 247 kidney recipients
who underwent transplant surgery at Mashhad University Montaserie Hospital, during 2012–2014. All patients were followed for
UTI during the 1st year after surgery. Results: 75 episodes of UTI developed by 152 pathogens in 56 (22.7%) of patients during 1‑year
follow‑up. 26.6% of total UTIs were diagnosed within the 1st month after transplantation. The most frequently isolated uropathogens
were Escherichia coli (55.3%, n = 84). The high rate of candiduria (8.5%) was observed, too. Conclusion: UTI is known as one of the
hospitalization reasons in kidney transplantation recipients. Defining appropriate antibiotic prophylaxis against bacterial and fungal
agents and early removal of urethral catheter are suggested to decrease posttransplantation complications.
Keywords :
Candiduria, Escherichia coli , follow‑up, kidney transplantation , urinary tract infection
