Author/Authors :
Dima, Mirabela Departments of Neonatology - Victor Babes University of Medicine and Pharmacy - Timisoara, Romania , Iacob, Daniela Departments of Neonatology - Victor Babes University of Medicine and Pharmacy - Timisoara, Romania , Marginean, Otilia Departments of Pediatrics - Victor Babes University of Medicine and Pharmacy - Timisoara, Romania , Iacob, Emil Radu Departments Pediatric Surgery - Victor Babes University of Medicine and Pharmacy - Timisoara, Romania
Abstract :
Neonatal sepsis (NS) is recognized as a leading global
public health challenge and has a fulminant and fatal
evolution if the treatment is not commenced promptly.
Neonatal infections annually claim lives of 1.4 million
neonates worldwide. Early‑onset NS (EONS) occurs
within 72 h of birth, while late‑onset NS (LONS) occurs
after the first 72 h of life and both are major causes of
infant mortality. Biomarkers have an important place
in the pathophysiology of sepsis; they can indicate
the presence, absence, or severity of sepsis and can
differentiate bacterial from viral and fungal infection
and systemic sepsis from local infection.
Keywords :
biological , EONS , LONS , neonatal