Losartan risk for female in cisplatin‑induced nephrotoxicity

Blood pressure alteration and angiotensin receptor blocker treatment may influence cisplatin‑induced nephrotoxicity. Komaki et al.[1] in their cohort study concluded that “Lower blood pressure and the use of renin‑angiotensin system inhibitors were associated with the incidence of cisplatin nephrotoxicity” while Liu et al.[2] in their study mentioned that “Angiotensin‑converting enzyme inhibitor/angiotensin receptor blocker usage and administration of a single application of cisplatin were independent risk factors for cisplatin‑induced acute kidney injury in the elderly