Title of article :
Magnetic resonance imaging findings in diagnosis and prognosis of Wilson disease
Author/Authors :
Salari, Mehri Isfahan University of Medical Sciences , Fayyazi, Emad Isfahan University of Medical Sciences , Mirmosayyeb, Omid Isfahan University of Medical Sciences
Abstract :
Wilson disease (WD) is a rare autosomal recessive disorder characterized by excessive copper deposition in the body, principally in
the liver and the brain. There is a wide spectrum of clinical presentations, but the most significant and basic symptoms of the disease
can be divided into hepatic, neurologic, and psychiatric manifestations. Magnetic resonance imaging (MRI) provides more detailed
anatomical information than computed tomography of the brain, especially of the structure of the basal ganglia and brain stem. In
this review, we want to evaluate the correlation between MRI findings and clinical features of WD.
Keywords :
Hepatocerebral degeneration , magnetic resonance imaging , Wilson disease
Journal title :
Astroparticle Physics