Author/Authors :
Sayahi, A Young and Elite Research Club - Kazerun Branch, Islamic Azad University, Kazerun, Iran , Nowroozi-Asl, A Department of Clinical Sciences - Faculty of Veterinary Medicine - Kazerun Branch, Islamic Azad University, Kazerun, Iran , Fattahi, H Department of Pathobiology - Faculty of Veterinary Medicine - Kazerun Branch, Islamic Azad University, Kazerun, Iran
Abstract :
Diarrhea in calves is one of the most prevalent diseases the veterinarians encounter in practice. Diarrhea is
responsible for major economic damages in livestock husbandries. Escherichia coli (E.coli) has been regarded as
the main factor that causes white diarrhea in calves’ first three weeks of life. Antimicrobial treatment of E. coli is
difficult since these bacteria naturally show resistance against most antibiotics. The aim of the present study is to
investigate the antibacterial activity of aqueous extract of garlic on Escherichia coli isolated from calves with
diarrhea. This descriptive cross-sectional study was carried out to investigate the effect of aqueous extract of garlic
on 100 samples of calves with diarrhea collected from traditional and industrial livestock husbandries crops in
Kazerun during February and March 2016 and April 2017. The isolates susceptibility to different antibiotics was
tested by the disc diffusion method and the antibacterial activity of garlic extract was measured by MIC and MBC
methods. In this study, the highest resistance was seen against ampicillin and tetracycline (0± 0.4 mm, 0± 0.5 mm)
and the lowest resistance was against ciprofloxacin (40 ± 2/54 mm). The halo diameter formed by aquatic extract of
garlic was similar to streptomycin (15 ± 1/00 mm). In general, the results showed that garlic has the potentiality to
be used as an antimicrobial drug, especially in the treatment of E. coli-induced diarrhea in calves.
Keywords :
aquatic garlic extract , calf diarrhea , Escherichia coli , Kazerun
