Urogenital and other Associated Anomalies in Patients With Anorectal Malformations

Anorectal malformations (ARM) comprise a wide spectrum of diseases and associated anomalies. ARM are the major factors that contribute to high morbidity and mortality in neonates. The aim of this retrospective study was to review the incidence of urogenital and other associated anomalies in neonates in whom the diagnosis of ARM was confirmed between 2005 and 2010. We found cases of 58 patients with ARM; of these patients, 65.5% were boys and 17.2% were born prematurely. The mean birth weight was 2.8 kg (SD 0.5). The following anomalies associated with ARM were observed in 63.8% of the patients: urogenital (43.1%), cardiovascular (41.4%), sacrospinal (13.8%), limb (10.3%), and tracheoesophageal fistula (TEF; 6.9%) anomaly. Urogenital anomalies were more common than other anomalies among patients with high ARM (25 patients). ARM-associated urologic anomalies were found in 16 of 25 (64%) patients, and hydronephrosis was the most common (62%) urologic anomaly. Genital anomalies were detected in 9 of the 25 (36%) patients, and undescended testes (37.5%) and hypospadias (37.5%) were the most common genital anomalies. Detailed evaluation of associated anomalies, “VACTERl workup,” in the neonatal period is essential for newborns with ARM.