Abstract :
In the mid-1980’s, the Aarhus group headed by the two
pioneers in Nocturnal Enuresis research Jens-Christian
Djurhuus and Jens Peter Nørgaard, reported the first data
correlating the degree of Vesicoureteral Reflux (VUR) and
associated nephropathy to the presence of enuresis (1).
The material showed that one half of the patients with
reflux also had enuresis, and that in spite of identical demographics
and medical history, patients with enuresis
presented a significantly lower degree of reflux nephropathy,
leading to the hypothesis that enuresis might act as
a safety valve mechanism reducing the possibility of VUR
nephropathy.
