Title of article :
Klotho and Renal Fibrosis
Author/Authors :
Zununi Vahed, Sepide Faculty of Advanced Medical Sciences - Tabriz University of Medical Sciences, Tabriz , Nikasa, Parisa Faculty of Advanced Medical Sciences - Tabriz University of Medical Sciences, Tabriz , Ardalan, Mohammadreza Tabriz University of Medical Sciences, Tabriz
Abstract :
Renal fibrosis is a pathological condition that characterized by excessive accumulation of extracellular matrix (ECM) and it is a common pathway of progression in different renal diseases including chronic glomerulonephritis, diabetic nephropathy chronic allograft nephropathy and renal senescence (1, 2). In the process of renal fibrosis leukocyte infiltration, activation of fibroblasts and myofibroblasts, epithelial-mesenchymal transition (EMT) all have been identified as the major events (3).
Keywords :
Klotho Protein , Nephrogenic Fibrosing Dermopathy , Renal Insufficiency , Chronic , Fibrosis
Journal title :
Astroparticle Physics
