Author/Authors :
Farid, Reza Department of Immunology and Allergy - Ghaem Medical Center - Mashhad University of Medical Sciences, Mashhad , Jabbari Azad, Farahzad Department of Immunology and Allergy - Ghaem Medical Center - Mashhad University of Medical Sciences, Mashhad , Ebrahimi Atri, Ahmad Ferdowsi University of Mashhad, Mashhad , Baradaran Rahimi, Mahmoud Department of Immunology and Allergy - Ghaem Medical Center - Mashhad University of Medical Sciences, Mashhad , Khaledan, Asghar Tehran University, Tehran , Talaei-Khoei, Mojtaba Department of Immunology and Allergy - Ghaem Medical Center - Mashhad University of Medical Sciences, Mashhad , Ghafari, Javad Department of Immunology and Allergy - Ghaem Medical Center - Mashhad University of Medical Sciences, Mashhad , Ghasemi, Ramin Department of Immunology and Allergy - Ghaem Medical Center - Mashhad University of Medical Sciences, Mashhad
Abstract :
The aim of the present study was to examine the effects of a course of aerobic
exercise on pulmonary function and tolerance of activity in asthmatic patients.
Among the asthmatic patients, 36 patients (M= 16, F= 20) were chosen after clinical
examinations, pulmonary function test, skin prick test (SPT) for aeroallergen and a six
minute walk test (6MWT) on their own free will. A patient was said to have Exercise
Induced Asthma (EIA) when he/she fulfilled the following criteria; (1) FEV1 < 80%,
(2) 12% increase or more in FEV1 or PEF after short-acting ß2 agonist prescription and
(3) 15% decrease in FEV1 or PEF after 6MWT with 70% or 80% of maximum heart
rate. The patients were randomly put into two groups of case (M=8, F=10, Mean
age=27) and control (M=8, F=10, Mean age=29). Case group participated in eightweek
aerobic exercise plan, while control group had no plan of exercise. Pulmonary
function tests were done before and after the course of exercise.
There were significant changes in FEV1, FVC, PEF, FEF25-75%, MVV, RF and
6MWT between asthmatic patients of the two groups (P≤0.05), but FEV1/FVC showed
no significant change. Mean of changes in FEV1, FVC, PEF, FEF25-75%, MVV, RF and
6MWT were –25.56, -17.19, 32.09, -27.93, -22.18, 5.63 and –307.5 in case group
respectively while they were 6.2, 4.67, 1.96, 6.65, 15.56,-2.87 and 18.78 in the control
group.
This study shows that aerobic exercises in asthmatic patients lead to an
improvement in pulmonary functions. Aerobic exercise rehabilitation can be a
complement to medical treatment of asthma