Author/Authors :
Nabavizadeh, Hesamedin Department of Immunology - School of Medicine - Shiraz University of Medical Sciences, Shiraz , Karimi, Mehran Department of Hematology Research Center - School of Medicine - Shiraz University of Medical Sciences, Shiraz , Amin, Reza Department of Immunology - School of Medicine - Shiraz University of Medical Sciences, Shiraz
Abstract :
Polyclonal anti-thymocyte globulin (ATG) is used as
an immunosuppressive agent in the treatment of aplastic
anemia (AA). Serum sickness is a recognized side effect
of ATG. We observed abnormal skin manifestation in
patient with aplastic anemia who had been treated with
ATG. We conclude that abnormal immune function
caused by aplastic anemia and ATG and corticosteroids
may aggravate the signs of serum sickness.
