Author/Authors :
Kajbafzadeh, A Department of Pediatric Urology - Children’s Hospital Medical Center - Tehran University of Medical Sciences, Tehran , Espandar, L Department of Pediatric Urology - Children’s Hospital Medical Center - Tehran University of Medical Sciences, Tehran , Mehdizadeh, M Department of Pediatric Radiology - Children’s Hospital Medical Center - Tehran University of Medical Sciences, Tehran , Tajik, P Department of Pediatric Urology - Children’s Hospital Medical Center - Tehran University of Medical Sciences, Tehran , Mohseni, P Department of Pediatric Nephrology - Children’s Hospital Medical Center - Tehran University of Medical Sciences, Tehran
Abstract :
Background/Objectives:Ofcongenitalmalformationsofthecentralnervoussystem46%are
abnormalities of thespinal cord,which includesspinabifidaocculta (SBO).Theoccurrence
andsignificanceofspinabifidaoccultainpatientswithpersistentprimarynocturnalenuresis
(PPNE)wereevaluated.
MaterialsandMethods:BetweenJanuary2000andFebruary2001,109consecutivechildren
whohadnocturnalenuresismorethanoncea weekaftertheageof7 yearsforanuninterrupted
period of at least 3 months, with less than 50% reduction in wet nights despite
differenttreatmentsforatleast6 months,wereprospectivelyevaluatedforthepresenceof
associated spinabifidaocculta.The resultswere comparedwithdata from a group of40
normalchildren.
Results:Themeanagewas9.9yearsinPPNEpatientsand7.5yearsinnormalgroup.SBO
waspresentin86(78.9%)ofPPNEpatientsand10(25%)ofnormalchildren.Thisdifference
wasstatisticallysignificantusingchi-squaretest.(P-value< 0.001)
Conclusion:Spinabifidaoccultawasthoughttohavenoclinicalsignificancebutourresults
showed its significant higher rateamongPPNE patients. There isno direct causal relation
betweenspinabifidaoccultaandenuresis,apparently,butthe findingssuggesta common
developmentaletiology.
