Title of article
Lobular Carcinoma of Breast Presenting with Skin and Stomach Metastases
Author/Authors
Arab Kheradmand, Ali Department of Surgical Oncology - Cancer Institute - Tehran University of Medical Sciences, Tehran , Elyasinia, Fezzeh Department of Surgery - Tehran University of Medical Sciences, Tehran , Parsaei, Reza Department of Surgery - Tehran University of Medical Sciences, Tehran , Haidari, Ali Department of Pathology - Tehran University of Medical Sciences, Tehran
Pages
4
From page
37
To page
40
Abstract
Background: Skin metastases occur in 1-5% of solid tumors and are rarely the
presenting sign of internal malignancies. Certain features in skin lesions raise
suspicion of metastasis from solid tumors.
Case Presentation: In this article a 61-year-old woman is presented with
erythematous skin nodules in upper abdomen and chest. Histopathological
evaluation of lesions suggested metastatic carcinoma and a thorough search found
stomach signet cell adenocarcinoma and breast lobular carcinoma.
Immunohistochemical staining confirmed diagnosis of lobular carcinoma with
metastasis developed in skin and stomach.
Conclusion: Clinicians must be aware that malignancies can present by skin
metastases. Since breast and stomach cancer can both metastasize to skin,
immunohistochemistry evaluation is of great importance to diagnose the primary tumor
Keywords
breast cancer, , skin metastasis , Lobular carcinoma , stomach metastasis , Immunohistochemistry
Journal title
Astroparticle Physics
Record number
2434913
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