Author/Authors :
Kaviani, Ahmad Department of Surgery - Tehran University of Medical Sciences, Tehran , Mir, Mohammadreza Department of Surgery - Tehran University of Medical Sciences, Tehran , Daryani, Amir Department of Plastic Surgery - Shahid Beheshti University of Medical Sciences, Tehran , Bonyadi, Mahtab School of Medicine - Tehran University of Medical Sciences, Tehran , Ebrahimi, Mandana , Neishaboury, Mohamadreza Department of Surgery - Tehran University of Medical Sciences, Tehran , Montazeri, Ali
Abstract :
Background: Quality of life (QOL) is becoming an important indicator of
treatment efficacy in patients with breast cancer. Most previous studies have
compared patients' QOL following breast conserving surgery (BCS) and
mastectomy with or without reconstruction. Our aim was to assess the impact of
BCS versus oncoplastic breast surgery (OBS).
Methods: Selection of patients for BCS or OBS was performed according to
standard criteria e.g the breast and tumor size. The QOL was assessed by
employing EORTC QLQ-C3 and QLQ-BR23 questionnaires concurrently and
one year after the surgery. The QOL scores one year after the surgery were
compared between two groups using analysis of covariance, after adjusting for the
baseline values.
Results: A total of 120 patients with a mean age of 46.16±1.4 years were
enrolled in the study. BCS and OBS were the main surgical treatment techniques
in 57(47.5%) and 63(52.5%) patients, respectively.At the time of the last followup
visit, there were no differences between the two groups regarding functional
scales such as physical (P = 0.761), role (P = 0.356), emotional (P = 0.107),
cognitive (P = 0.051), and social functioning (P = 0.659). No differences were
observed between the two groups regarding nine symptom scales. Based on the
results of breast cancer specific module of the questionnaire, no differences were
observed in functional scales and symptoms with the exception of arm symptoms
whichwere less common inOBS group (P= 0.023)
Conclusions: Based on the results of the current study, it could be suggested
that there are no significant differences in the in scores of QOL components
between patientswho received BCS orOBS.