Author/Authors :
Amini, Mahnaz Faculty of Medicine - Mashhad University of Medicine Sciences, Mashhad , Mirfeizi, Zahra School of Medicine - Mashhad University of Medical Sciences, Mashhad , Rafatpanah, Houshang Faculty of Medicine - Mashhad University of Medical Sciences, Mashhad , Ghofraniha, Leila Faculty of Medicine - Mashhad University of Medicine Sciences, Mashhad , Mohammadzadeh Lari, Shahrzad Faculty of Medicine - Mashhad University of Medicine Sciences, Mashhad , Eslami, Saeid School of Pharmacy - Mashhad University of Medical Sciences, Mashhad , Esmaily, Habibollah Department of Biostatistics - School of Health - Mashhad University of Medical Sciences, Mashhad
Abstract :
Objective: The effects of serum vitamin D levels on the evolution or severity of asthma have been widely researched; however, conflicting results have been achieved. This study was designed to evaluate the relationship between serum vitamin D levels and pulmonary function tests in asthmatic and non-asthmatic people with vitamin D deficiency.
Materials and Methods: This was a prospective cross-sectional study on healthy adults and asthmatic patients. Standard spirometry and serum 25-hydroxyvitamin D test were performed for all participants.
Results: Forty asthmatic patients and 40 healthy controls were tested. The mean age of participants was 42.86 ± 1.6. High prevalence of vitamin D deficiency was found in both the asthmatic and control groups. No significant correlation was found between serum vitamin D levels and spirometry parameters in either of the groups (P = 0.83).
Conclusion: Serum levels of 25-hydroxyvitamin D were not correlated with the severity of asthma as evaluated by pulmonary function tests in asthmatics.
