Synthesis, physicochemical probe and antimicrobial assay of bis-chalcone, pyrazole, amino-pyrimidine and malononitrile derivatives from five and six membered cyclic imides

Heterocyclic imides greately involves in the development of organic synthesis. Coloured flavonoids like bis-chalcones are formed by microwave assisted solvent free route using phenyl succinimide, glutarimide and vanilln. To achieve the pyrazole and amino-pyrimidine derivatives by the cyclization of bis-chalcone with hydrazine hydrate and guanidine nitrate via microwave method. Then dimalononitriles were produced by active methylene group of dinitrile with cyclic imides. Hence the physicodhemical properties and antimicrobial actions persisted by moderate to high potencies.